2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid
CAS: 68399-81-5
Molecular Formula: C7H17NO7S
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid - Names and Identifiers
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid - Physico-chemical Properties
| Molecular Formula | C7H17NO7S |
| Molar Mass | 259.28 |
| Density | 1.07607 g/cm3(Temp: 25.00 °C) |
| Melting Point | 224-229°C (dec.) |
| Water Solubility | soluble |
| Solubility | H2O: 1M at20°C, clear, colorless |
| Appearance | White powder |
| Color | Off-white to yellow |
| Merck | 13,9148 |
| BRN | 2113949 |
| pKa | 7.6(at 25℃) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.589 |
| MDL | MFCD00038352 |
| Use | Biological buffer |
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29221990 |
| Hazard Class | IRRITANT |
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid - Reference Information
| application | N-tris (hydroxymethyl) methinoate -2-hydroxypropanesulfonic acid can be used as an ionic buffer, and can also be used as an organic synthesis intermediate and a pharmaceutical intermediate. It is mainly used in laboratory research and development processes and chemical and pharmaceutical synthesis processes. |
| Preparation | N-tris (hydroxymethyl) methionine-2-hydroxypropanesulfonic acid is prepared as follows: 242.28 grams (2 moles) of tris (hydroxymethyl) aminomethane, A mixture of 500 ml of water and 196.5g (1 mol) of sodium 3-chloro-2-hydroxypropyl sulfonate is put into a 1 liter 2-neck flask with a stirrer and condenser. Stir the mixture vigorously under reflux for 3 hours. After cooling to 25°C, the solution is passed through a cation exchange resin column in the form of Dowex50 and hydrogen to remove sodium cations and form free acids. The eluent from the column evaporates into heavy oil under vacuum. After dilution with alcohol, the product crystallizes from the solution, is filtered and washed with alcohol and dried. 160 grams of the white product N-tris (hydroxymethyl) methine-2-hydroxypropanesulfonic acid was obtained. |
| use | biological buffer |
| EPA chemical information | information provided by: ofmpub.epa.gov (external link) |
Last Update：2024-04-09 19:05:03
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Product Name: 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid Request for quotationCAS: 68399-81-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid Request for quotationCAS: 68399-81-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: TAPSO Visit Supplier Webpage Request for quotationCAS: 68399-81-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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